Mitoxantrone

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Chemical Structure : Mitoxantrone

CAS No.: 65271-80-9

Catalog No.: PC-24867Not For Human Use, Lab Use Only.

Mitoxantrone is a specific small molecule inhibitor of USP11 with IC50 of 3.15 uM, impacts PDA cell survival with an IC50<10 nM, also is a potent topoisomerase II inhibitor and inhibits protein kinase C (PKC) activity with IC50 of 8.5 uM.

Packing	Price	Stock
25 mg	$28	In stock
50 mg	$45	In stock
100 mg	$65	In stock
250 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	444.49
Formula	C22H28N4O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione

References

1. Burkhart RA, et al. Mol Cancer Res. 2013 Aug;11(8):901-11.

2. Jacko AM, et al. Cell Death Dis. 2016 Nov 17;7(11):e2474.

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Mitoxantrone

Biological Activity

Physicochemical Properties

References

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