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Hyperoside

Chemical Structure : Hyperoside

CAS No.: 482-36-0

Hyperoside

Catalog No.: PC-24885Not For Human Use, Lab Use Only.

Hyperoside is a naturally occurring flavonol glycoside with anti-colitis and anticancer potential, also is a USP18 inhibitor that directly targets the USP18 IBB1 domain (BLI KD=7.04 uM), hyperoside inhibits PRRSV proliferation via the TLR4/NF-kappaB and p62-Nrf2-Keap1 signaling pathways.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Hyperoside is a naturally occurring flavonol glycoside with anti-colitis and anticancer potential, also is a USP18 inhibitor that directly targets the USP18 IBB1 domain (BLI KD=7.04 uM), hyperoside inhibits PRRSV proliferation via the TLR4/NF-kappaB and p62-Nrf2-Keap1 signaling pathways.

Physicochemical Properties

M.Wt 464.38
Formula C21H20O12
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

References

1. Ye S, et al. Cell Death Dis. 2025 Jun 13;16(1):448.

2. Wang T, et al. Microbiol Spectr. 2025 Jun 12:e0310724.

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