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Chemical Structure : P22077
CAS No.: 1247819-59-5
Catalog No.: PC-21881Not For Human Use, Lab Use Only.
P22077 is a selective cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with IC50 of 8.01 uM, also inhibits USP47 with IC50 of 8.47 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $148 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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P22077 is a selective cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with IC50 of 8.01 uM, also inhibits USP47 with IC50 of 8.47 uM.
P22077 oes not significantly affect other DUBs (USP1, 4, 8, 10, 16, 19, 22, 24, 28, 48, VCIP135, OTUD5, BAP1, ATXN3, YOD1, and UCH-L5) at 25 uM.
| M.Wt | 315.31 | |
| Formula | C12H7F2NO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-(5-((2,4-Difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone |
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1. Altun M, et al. Chem Biol. 2011 Nov 23;18(11):1401-12.
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