P22077 | USP7/USP47 inhibitor | Probechem Biochemicals

Chemical Structure : P22077

CAS No.: 1247819-59-5

P22077 (P 22077)

Catalog No.: PC-21881Not For Human Use, Lab Use Only.

P22077 is a selective cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with IC50 of 8.01 uM, also inhibits USP47 with IC50 of 8.47 uM.

Packing	Price	Stock
10 mg	$88	In stock
25 mg	$148	In stock
50 mg	$218	In stock
100 mg		Get quote

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Biological Activity

P22077 is a selective cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with IC50 of 8.01 uM, also inhibits USP47 with IC50 of 8.47 uM.
P22077 oes not significantly affect other DUBs (USP1, 4, 8, 10, 16, 19, 22, 24, 28, 48, VCIP135, OTUD5, BAP1, ATXN3, YOD1, and UCH-L5) at 25 uM.

Physicochemical Properties

M.Wt	315.31
Formula	C12H7F2NO3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(5-((2,4-Difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone

References

1. Altun M, et al. Chem Biol. 2011 Nov 23;18(11):1401-12.

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P22077 (P 22077)

Biological Activity

Physicochemical Properties

References

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