Catalog No.: PC-22313Not For Human Use, Lab Use Only.
USP10 inhibitor D1 is a potent, selective small molecule ubiquitin-specific protease 10 (USP10) inhibitor with IC50 of 7.2 uM, KD of 5.24 uM in microscale thermophoresis (MST)-based binding assay.
USP10 inhibitor D1 is a potent, selective small molecule ubiquitin-specific protease 10 (USP10) inhibitor with IC50 of 7.2 uM, KD of 5.24 uM in microscale thermophoresis (MST)-based binding assay.
USP10 inhibitor D1 does not inhibit the deubiquitinase activity of USP7 at 10 uM.
USP10 inhibitor D1 inhibits the proliferation of hepatocellular carcinoma cell (Huh-7, IC50=2.3 uM) by inducing cell apoptosis and S-phase arrest.
USP10 inhibitor D1 inducing the degradation of USP10-related substrate protein by inhibiting USP10.
