LDN-91946 | UCHL1 inhibitor | Probechem Biochemicals

Chemical Structure : LDN-91946

CAS No.: 439946-22-2

LDN-91946 (LDN91946)

Catalog No.: PC-61936Not For Human Use, Lab Use Only.

LDN-91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM, exhibits no activity against other cysteine hydrolase (UCH-L3, TGase 2, papain and caspase-3).

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100 mg	$98	In stock
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Biological Activity

LDN-91946 is a selective, uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with Ki of 2.8 uM, exhibits no activity against other cysteine hydrolase (UCH-L3, TGase 2, papain and caspase-3).

Physicochemical Properties

M.Wt	316.32
Formula	C17H12N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-amino-2-(benzoyl)-6-oxo-7H-thieno[3,2-e]pyridine-5-carboxylic acid

References

1. Mermerian AH, et al. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3729-32.

2. Coulombe J, et al. Front Aging Neurosci. 2014 Jun 19;6:129.

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LDN-91946 (LDN91946)

Biological Activity

Physicochemical Properties

References

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