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Chemical Structure : USP10-IN-3
Catalog No.: PC-61934Not For Human Use, Lab Use Only.
USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
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USP10-IN-3 is a HBX19818 analog, potent and selective USP10 inhibitor, but does not inhibit USP7 (IC50>100 uM).
USP10-IN-3 demonstrates specificity for FLT3- mutant MOLM13-luc+, MOLM14 and MV4,11 cell lines relative to the FLT3-null TF-1 cell line and to other leukemia lines not driven by FLT3.
| M.Wt | 401.979 | |
| Formula | C23H32ClN3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Weisberg EL, et al. Nat Chem Biol. 2017 Dec;13(12):1207-1215.
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