| Cat. No. |
Product Name |
Information |
| PC-49295 |
BML-259
CDK5 inhibitor
|
BML-259 (BML259) is a potent, specific Cdk5/p25 and Cdk2 inhibitor with IC50 of 64 and 98 nM, respectively. |
| PC-47009 |
Cdk5 inhibitor 25-106
Cdk5/p35 inhibitor
|
Cdk5 inhibitor 25-106 is a potent, brain-penetrant inhibitor of Cdk5/p35 activity with IC50 of 178 nM. |
| PC-38769 |
ERP1.28a
CDC-7 inhibitor
|
ERP1.28a is a selective, small molecule inhibitor of cell division cell cycle kinase 7 (CDC-7) with IC50 of 140 nM, decreases the enhanced TDP-43 phosphorylation in cells derived from TDP-43-related pathogenesis such as FTLD and ALS. |
| PC-38768 |
ERP1.14a
CDC-7 inhibitor
|
ERP1.14a is a selective, small molecule inhibitor of cell division cell cycle kinase 7 (CDC-7) with IC50 of 125 nM, decreases the enhanced TDP-43 phosphorylation in cells derived from TDP-43-related pathogenesis such as FTLD and ALS. |
| PC-38750 |
ZNL-05-044
CDK11 inhibitor
|
ZNL-05-044 is a potent, selective CDK11 inhibitor with Kd of 69 nM (CDK11A), shows significantly kinome-wide selectivity. ZNL-05-044 treatment leads to G2/M cell cycle arrest, impacts CDK11-dependent mRNA splicing in cells. |
| PC-38645 |
Cimpuciclib
CDK inhibitor
|
Cimpuciclib is a cyclin-dependent kinase(CDK) inhibitor with antineoplastic activity. |
| PC-38600 |
GSK-3/CDK5/CDK2-IN-1
GSK-3/CDK5/CDK2 inhibitor
|
GSK-3/CDK5/CDK2-IN-1 is an inhibitor of CDK5, CDK2 and GSK-3, inhibits the phosphorylation of Cdk5 peptide substrate phosphorylation with IC50 of <50 uM. |
| PC-38355 |
Dalpiciclib
CDK4/6 inhibitor
|
Dalpiciclib (SHR6390) is an orally bioavailable, small molecule CDK4/6 inhibitor, strongly inhibits tumor proliferation of ESCC in vitro and in vivo. |
| PC-73446 |
Tanuxiciclib
CDK inhibitor
|
Tanuxiciclib is a potent cyclin dependent kinase (CDK) inhibitor. |
| PC-73414 |
Eciruciclib
CDK inhibitor
|
Eciruciclib is a potent cyclin dependent kinase (CDK) inhibitor with antineoplastic activities. |
| PC-73257 |
ASP9822
CDK7 inhibitor
|
ASP9822 is a novel potent selective CDK7 inhibitor with IC50 of 4.3 nM, with anti-cancer activity. |
| PC-72467 |
LY3405105
CDK7 inhibitor
|
LY3405105 (LY-3405105) is a potent, selective, orally active CDK7 inhibitor with an IC50 of 92.8 nM, shows potential antineoplastic activity. |
