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CDK2 inhibitor 73

Chemical Structure : CDK2 inhibitor 73

CAS No.: 2079895-42-2

CDK2 inhibitor 73 (CDK2-IN-4)

Catalog No.: PC-61136Not For Human Use, Lab Use Only.

CDK2 inhibitor 73 (CDK2-IN-4) is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CDK2 inhibitor 73 (CDK2-IN-4) is a potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).

Physicochemical Properties

M.Wt 442.497
Formula C23H18N6O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((6-([1,1'-biphenyl]-3-yl)-9H-purin-2-yl)amino) benzenesulfonamide

References

1. Coxon CR, et al. J Med Chem. 2017 Mar 9;60(5):1746-1767.

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