TP-1287 | CDK9 inhibitor | Probechem Biochemicals

Chemical Structure : TP-1287

CAS No.: 2044686-42-0

Catalog No.: PC-25402Not For Human Use, Lab Use Only.

TP-1287 is a prodrug of Alvocidib (Flavopiridol, HMR-1275), is an orally active CDK9 inhibitor.

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Biological Activity

TP-1287 is a prodrug of Alvocidib (Flavopiridol, HMR-1275), is an orally active CDK9 inhibitor.

M.Wt	481.82
Formula	C21H21ClNO8P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-Chlorophenyl)-5-hydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4-oxo-4H-chromen-7-yl dihydrogen phosphate

1. Tyagi E, et al. Blood, 2018, 132: 3269.

2. Kim W, et al. Cancer Research. 2017, 77(13_Supplement): 5133-5133.