Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Apoptosis-Bcl-2-TUDCA
TUDCA

Chemical Structure : TUDCA

CAS No.: 14605-22-2

TUDCA (Tauroursodeoxycholic acid)

Catalog No.: PC-22111Not For Human Use, Lab Use Only.

Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate, prevents Bax translocation both in vitro and in vivo, thereby preserving mitochondrial function and suppressing apoptosis.

Packing Price Stock Quantity
50 mg $68 In stock
100 mg $98 In stock
200 mg $138 In stock
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate, prevents Bax translocation both in vitro and in vivo, thereby preserving mitochondrial function and suppressing apoptosis.
TUDCA inhibits nuclear factor-kappa B (NF-κB) activation in glial cells.
TUDCA shows anti-inflammatory effect by inducing TGF-β pathway.
TUDCA also inhibits TNFα-induced lipolysis.

Physicochemical Properties

M.Wt 499.71
Formula C26H45NO6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid

References

1. Romero-Ramirez L, et al. Neural Regen Res. 2017 Jan;12(1):62-63.

2. Xia W, et al. Mol Med Rep. 2017 Apr;15(4):1753-1758.

3. Rani S, et al. PLoS One. 2017 Apr 20;12(4):e0176071.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: