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Chemical Structure : TUDCA
CAS No.: 14605-22-2
Catalog No.: PC-22111Not For Human Use, Lab Use Only.
Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate, prevents Bax translocation both in vitro and in vivo, thereby preserving mitochondrial function and suppressing apoptosis.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $68 | In stock | |
| 100 mg | $98 | In stock | |
| 200 mg | $138 | In stock | |
| 500 mg | Get quote | ||
| 1 g | Get quote |
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Tauroursodeoxycholic acid (TUDCA) is a neuroprotective bile conjugate, prevents Bax translocation both in vitro and in vivo, thereby preserving mitochondrial function and suppressing apoptosis.
TUDCA inhibits nuclear factor-kappa B (NF-κB) activation in glial cells.
TUDCA shows anti-inflammatory effect by inducing TGF-β pathway.
TUDCA also inhibits TNFα-induced lipolysis.
| M.Wt | 499.71 | |
| Formula | C26H45NO6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid |
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1. Romero-Ramirez L, et al. Neural Regen Res. 2017 Jan;12(1):62-63.
2. Xia W, et al. Mol Med Rep. 2017 Apr;15(4):1753-1758.
3. Rani S, et al. PLoS One. 2017 Apr 20;12(4):e0176071.
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