CCT373567 | BCL6 inhibitor | Probechem Biochemicals

Chemical Structure : CCT373567

CCT373567 (CCT 373567)

Catalog No.: PC-20626Not For Human Use, Lab Use Only.

CCT373567 is a potent, selective and cell-active BCL6 inhibitor with IC50 of 2.9 nM in TR-FRET assays, and 25.9 nM in NanoBRET cellular inhibition assays.

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Biological Activity

CCT373567 is a potent, selective and cell-active BCL6 inhibitor with IC50 of 2.9 nM in TR-FRET assays, and 25.9 nM in NanoBRET cellular inhibition assays.

Physicochemical Properties

M.Wt	547.00
Formula	C26H29ClF2N6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C1N(C)C2=C(C=C(NC3=NC(N4C[C@@H](O)C[C@@H](C)C4)=NC=C3Cl)C=C2)C5=C1OCC(F)(F)[C@H](C6CC6)N5

References

1. Alice C Harnden, et al. J Med Chem. 2023 Apr 7. doi: 10.1021/acs.jmedchem.3c00155.

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CCT373567 (CCT 373567)

Biological Activity

Physicochemical Properties

References

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