Chemical Structure : VX-702
CAS No.:
745833-23-2
VX-702
(VX702;VX 702)
Catalog No. : PC-42563Not For Human Use, Lab Use Only.
VX-702 is a potent, selective, second generation p38 MAPK inhibitor with IC50 of 4-20 nM for p38α.
Packing Price Stock Quantity 10 mg $128 In stock 0 1 2 3 4 5 25 mg $198 In stock 0 1 2 3 4 5 50 mg $298 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4256301
Biological Activity
VX-702 is a potent, selective, second generation p38 MAPK inhibitor with IC50 of 4-20 nM for p38α.
Physicochemical Properties
M.Wt
404.3178
Formula
C19H12F4N4O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 42 mg/mL
Chemical Name/SMILES
3-Pyridinecarboxamide, 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-
References
1. Kuliopulos A, et al. Thromb Haemost.
2. Damjanov N, et al. Arthritis Rheum.
3. Ding C. Curr Opin Investig Drugs. 2006 Nov;7(11):1020-5.
4. Matsushita T, et al. Am J Pathol. 2017 Apr;187(4):841-850.
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