MAPK13 inhibitor NuP-4

Chemical Structure : MAPK13 inhibitor NuP-4

Catalog No.: PC-23047Not For Human Use, Lab Use Only.

MAPK13 inhibitor NuP-4 is a potent, selective MAPK13 inhibitor with IC50 of 15 nM, with no MAPK14 inhibition.

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Biological Activity

MAPK13 inhibitor NuP-4 is a potent, selective MAPK13 inhibitor with IC50 of 15 nM, with no MAPK14 inhibition.
NuP-4 down-regulates basal-epithelial stem cell reprogramming, structural remodeling, and pathophysiology equivalently to Mapk13 gene-knockout in mouse and mouse organoid models of post-viral lung disease.
NuP-4 treatment can directly control cytokine-stimulated growth, immune activation, and mucinous differentiation in human basal-cell organoids.

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

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