| Cat. No. |
Product Name |
Information |
| PC-42717 |
Vipadenant
A2AR antagonist
|
Vipadenant (BIIB014) is a potent and selective A2A adenosine receptor antagonist with Ki of 1.3 nM. |
| PC-42729 |
Preladenant
A2AR antagonist
|
Preladenant (SCH420814) is a potent and highly selective adenosine A2A receptor competitive antagonist with Ki of 1.1 nM. |
| PC-42728 |
Istradefylline
A2AR antagonist
|
Istradefylline (KW6002) is a potent and highly selective A2A receptor antagonist with Ki of 2.2 nM. |
| PC-45527 |
APNEA
A3AR agonist
|
APNEA is a non-selective agonist of adenosine A3 receptor, has a high affinity for the adenosine A1 and A3 receptors. |
| PC-45624 |
AB-MECA
A3AR agonist
|
AB-MECA is a high affinity A3 adenosine receptor (A3AR) agonist with binding Ki of 430.5 nM for human A3 receptors in CHO cells. |
| PC-23389 |
SLV320
Adenosine A1 receptor antagonist
|
Derenofylline (SLV320) is a potent, selective and orally active adenosine A1 receptor antagonist with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. |
| PC-23365 |
TC-G 1004
A2A receptor antagonist
|
TC-G 1004 is a potent, selective orally active A2A adenosine receptor (A2A R) antagonist, with Ki values of 0.44 nM and 80 nM for hA2A and hA1, respectively. |
| PC-22840 |
DPCPX
Adenosine A1 receptor antagonist
|
DPCPX (PD116948) is a highly potent and selective adenosine A1 receptor antagonist with Ki of 0.46 nM, >500-fold selective over A2 receptor. |
| PC-22838 |
AR-001
Adenosine A1 receptor agonist
|
AR-001 is a selective adenosine A1 receptor agonist with EC50 of 9.35 uM in HEK293-aeqα15/ADORA1 cells, increases adenosine A1 receptor expression and mRNA level in the hypothalamus of mice, exhibits hypnotic efficacy. |
| PC-22753 |
MRS-1706
A2BR antagonist
|
MRS-1706 (MRS1706) is a potent and selective adenosine A2B receptor (A2BR) inverse agonist / antagonist with Ki of 1.39 nM, >100-fold selective over A2A, A1 and A3 receptors. |
| PC-22524 |
MRS1754
A2BR antagonist
|
MRS 1754 is a potent, adenosine receptor A2BAR selective antagonist with Ki of 1.97 nM, 205-, 255-, and 289-fold selective for the human A2BARs vs. human A1/A2A/A3 ARs, respectively. |
| PC-22361 |
LUF5834
A2AR agonist
|
LUF5834 is a potent, selective, non-adenosine adenosine A1 receptor adenosine receptor (A2BR) partial agonist with EC50 of 12 nM (hA2B), 45-fold selective over hA3, also shows high affinity with Ki of 2.6 nM and 28 nM for hA1 and hA2A, respectively. |
