| Cat. No. |
Product Name |
Information |
| PC-21513 |
TRR469
A1AR modulator
|
TRR469 is a potent, selective adenosine A1 receptor (A1AR) positive allosteric modulator with pKb of 5.36, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. |
| PC-21512 |
VCP171
A1AR PAM
|
VCP171 is a selective adenosine A1 receptor (A1AR) positive allosteric modulator (PAM), inhibits eEPSC amplitude of nerve-injury versus control animals in both lamina I and lamina II neurons. |
| PC-21510 |
MRS7935
A1AR modulator
|
MRS7935 is a potent, selective positive allosteric modulator (PAM) of A1 adenosine receptor (A1AR) with EC50 of 1.43 uM. |
| PC-20642 |
I-ABOPX
A3AR antagonist
|
I-ABOPX is a potent, selective A3 adenosine receptor (A3AR) antagonist with high affinity for both the ovine (Ki=3 nM) and human (Ki=19 nM) A3 receptors. |
| PC-20641 |
MRS1191
A3AR antagonist
|
MRS1191 (MRS-1191) is a potent and selective A3 adenosine receptor (A3AR) antagonist with Ki of 32 nM, shows no acitivity against A2A, A2B, A1 receptors (Ki>10 uM). |
| PC-20640 |
QAF-805
A2BR antagonist
|
QAF-805 (QAF805) is a potent, dual adenosine-A2B receptor and adenosine-A3 receptor antagonist with Ki of 3.4 nM (A2B). |
| PC-20639 |
KF26777
A3AR antagonist
|
KF-26777 (KF26777) is a potent and selective adenosine A3 receptor antagonist with Ki of 0.2 nM (human A3 receptor). |
| PC-20638 |
LAS101057
A2BR antagonist
|
LAS101057 (LAS 101057) is a potent, selective, and orally efficacious A2B adenosine receptor antagonist with Ki of 24 nM (human A2B). |
| PC-20546 |
PSB-1115
A2B antagonist
|
PSB-1115 (PSB1115) is a potent, selective adenosine A2B receptor antagonist with binding Ki of 53.4 nM (recombinant human A2B receptor), 40- and 400-fold selectivity over A1 and A2A receptors. |
| PC-20111 |
ASP5854
A1/A2A receptor antagonist
|
ASP5854 (ASP-5854) is a potent adenosine A(1) and A(2A) receptor dual antagonist with binding Ki of 9.03 and 1.76 nM for human A(1) and A(2A) receptors, respectively. |
| PC-20110 |
SCH-442416
A2AR antagonist
|
SCH-442416 (SCH442416) is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR) with Ki 0.048 nM and 0.5 nM for human and rat A2AR, respectively. |
| PC-20102 |
KW-6356
A2A receptor antagonist
|
KW-6356 (Sipagladenant) is a potent and selective adenosine A2A receptor antagonist/inverse agonist with pKi value of9.93 for human A2A receptor. |
