Inupadenant | A2AR antagonist | Probechem Biochemicals

Chemical Structure : Inupadenant

Inupadenant (EOS-850, EOS100850)

Catalog No.: PC-38365Not For Human Use, Lab Use Only.

Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

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Biological Activity

Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

Physicochemical Properties

M.Wt	604.652
Formula	C25H26F2N8O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-5-amino-3-(2-(4-(2,4-difluoro-5-(2-(methylsulfinyl)ethoxy)phenyl)piperazin-1-yl)ethyl)-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one

References

1. Laurence Buisseret, et al. Journal of Clinical Oncology, Volume 39, Issue 15_suppl.

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Inupadenant (EOS-850, EOS100850)

Biological Activity

Physicochemical Properties

References

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