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Inupadenant

Chemical Structure : Inupadenant

CAS No.: 2246607-08-7

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Inupadenant (EOS-850, EOS100850)

Catalog No.: PC-38365Not For Human Use, Lab Use Only.

Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Inupadenant (EOS-850, EOS100850) is a non brain-penetrant, potent and highly selective small molecule antagonist of adenosine A2a receptor (A2AR), shows activity at the high adenosine concentrations found in tumors.

    Physicochemical Properties

    M.Wt 604.652
    Formula C25H26F2N8O4S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (S)-5-amino-3-(2-(4-(2,4-difluoro-5-(2-(methylsulfinyl)ethoxy)phenyl)piperazin-1-yl)ethyl)-8-(furan-2-yl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one

    References

    1. Laurence Buisseret, et al. Journal of Clinical Oncology, Volume 39, Issue 15_suppl.

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