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APNEA

Chemical Structure : APNEA

CAS No.: 89705-21-5

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APNEA (N6-[2-(4-Aminophenyl)ethyl]adenosine)

Catalog No.: PC-45527Not For Human Use, Lab Use Only.

APNEA is a non-selective agonist of adenosine A3 receptor, has a high affinity for the adenosine A1 and A3 receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

APNEA is a non-selective agonist of adenosine A3 receptor, has a high affinity for the adenosine A1 and A3 receptors.
APNEA (0.0039-1 mg/kg) enhances the protective activity of carbamazepine.
APNEA dose-dependently increase the sustained (4 min) Ca2+ influx into rat cortical synaptosomes.

Physicochemical Properties

M.Wt 386.4051
Formula C18H22N6O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Adenosine, N-[2-(4-aminophenyl)ethyl]-

References

1. Borowicz KK, et al. Eur J Pharmacol. 1997 May 30;327(2-3):125-33.

2. Hannon JP, et al. J Pharmacol Exp Ther. 2002 Aug;302(2):725-30.

3. Li SN, et al. Neurochem Res. 2000 Apr;25(4):457-9.

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