Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Adenosine Receptor-Istradefylline
Istradefylline

Chemical Structure : Istradefylline

CAS No.: 155270-99-8

Istradefylline (KW 6002;KW-6002;KW6002)

Catalog No.: PC-42728Not For Human Use, Lab Use Only.

Istradefylline (KW6002) is a potent and highly selective A2A receptor antagonist with Ki of 2.2 nM.

Packing Price Stock Quantity
10 mg $68 In stock
25 mg $108 In stock
50 mg $168 In stock
100 mg $238 In stock
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Istradefylline (KW6002) is a potent and highly selective A2A receptor antagonist with Ki of 2.2 nM.
KW6002 significantly increases the total counts of turning induced by apomorphine at doses 1 mg/kg, p.o.
KW6002 also potentiates the rotational behavior induced by L-DOPA at a dose of 3 mg/kg, p.o.

Physicochemical Properties

M.Wt 384.429
Formula C20H24N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: < 6 mg/mL

Chemical Name/SMILES

1H-Purine-2,6-dione, 8-[(1E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl-

References

1. Koga K, et al. Eur J Pharmacol. 2000 Nov 24;408(3):249-55.

2. Chen JF, et al. J Neurosci. 2001 May 15;21(10):RC143.

3. Ochi M, et al. Neuroscience. 2000;100(1):53-62.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: