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Chemical Structure : Istradefylline
CAS No.: 155270-99-8
Catalog No.: PC-42728Not For Human Use, Lab Use Only.
Istradefylline (KW6002) is a potent and highly selective A2A receptor antagonist with Ki of 2.2 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $68 | In stock | |
| 25 mg | $108 | In stock | |
| 50 mg | $168 | In stock | |
| 100 mg | $238 | In stock | |
| 250 mg | Get quote |
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Istradefylline (KW6002) is a potent and highly selective A2A receptor antagonist with Ki of 2.2 nM.
KW6002 significantly increases the total counts of turning induced by apomorphine at doses 1 mg/kg, p.o.
KW6002 also potentiates the rotational behavior induced by L-DOPA at a dose of 3 mg/kg, p.o.
| M.Wt | 384.429 | |
| Formula | C20H24N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: < 6 mg/mL |
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| Chemical Name/SMILES |
1H-Purine-2,6-dione, 8-[(1E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-3,7-dihydro-7-methyl- |
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1. Koga K, et al. Eur J Pharmacol. 2000 Nov 24;408(3):249-55.
2. Chen JF, et al. J Neurosci. 2001 May 15;21(10):RC143.
3. Ochi M, et al. Neuroscience. 2000;100(1):53-62.
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