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Chemical Structure : SLV320
CAS No.: 251945-92-3
Catalog No.: PC-23389Not For Human Use, Lab Use Only.
Derenofylline (SLV320) is a potent, selective and orally active adenosine A1 receptor antagonist with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively.
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| 25 mg | $198 | In stock | |
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Derenofylline (SLV320) is a potent, selective and orally active adenosine A1 receptor antagonist with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively.
SLV320 displays 200-4000 fold selectivity versus other adenosine receptor subtypes.
SLV320 suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats with 5/6 nephrectomy.
| M.Wt | 308.39 | |
| Formula | C18H20N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
rel-(1r,4r)-4-((2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexan-1-ol |
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1. Kalk P, et al. Br J Pharmacol. 2007 Aug;151(7):1025-32.
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