KUNB106 | Hsp90β inhibitor | Probechem Biochemicals

Chemical Structure : KUNB106

Catalog No.: PC-22570Not For Human Use, Lab Use Only.

KUNB106 is a potent, highly selective Hsp90β inhibitor with KD of 91 nM, >275-fold selectivity vs. other isoforms.

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Biological Activity

KUNB106 is a potent, highly selective Hsp90β inhibitor with KD of 91 nM, >275-fold selectivity vs. other isoforms.

M.Wt	462.59
Formula	C27H34N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-(4-hydroxypiperidin-1-yl)-3-propyl-6-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)isoquinolin-1(2H)-one

1. Mishra, S. J. et al. J. Med. Chem. 64, 1545–1557.

2. Duron DI, et al. Sci Rep. 2024 Jun 26;14(1):14715.