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TRC051384

Chemical Structure : TRC051384

CAS No.: 867164-40-7

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TRC051384 (TRC-051384)

Catalog No.: PC-42416Not For Human Use, Lab Use Only.

TRC051384 is a potent heat shock protein 70 (HSP70) inducer, involves HSF1 activation.

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10 mg $128 In stock
25 mg $218 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TRC051384 is a potent heat shock protein 70 (HSP70) inducer, involves HSF1 activation.
TRC051384 significantly reduces stroke associated neuronal injury and disability in a rat model of transient ischemic stroke.
TRC051384 delays thrombus formation without increased bleeding risk in mice.

Physicochemical Properties

M.Wt 465.54
Formula C25H31N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥100 mg/mL
Chemical Name/SMILES

Urea, N-[2-(4-morpholinyl)ethyl]-N'-[4-[3-[6-(4-morpholinyl)-2-pyridinyl]-1-oxo-2-propen-1-yl]phenyl]-

References

1. Mohanan A, et al. Neuropharmacology. 2011 May;60(6):991-9.

2. Allende M, et al. Cardiovasc Res. 2016 Jun 1;110(3):309-18.

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