Chemical Structure : VX-984
CAS No.: 1476074-39-1
Catalog No.: PC-61971Not For Human Use, Lab Use Only.
VX-984 (M9831) is a potent, selective inhibitor of DNA-PK with IC50 of 88 nM for inhibition of DNA-PKcs autophosphorylation (Ser2056) in A549 lung cancer cells, with good selectivity versus other PI3K family members.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $148 | In stock | |
| 5 mg | $258 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
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VX-984 (M9831) is a potent, selective inhibitor of DNA-PK with IC50 of 88 nM for inhibition of DNA-PKcs autophosphorylation (Ser2056) in A549 lung cancer cells, with good selectivity versus other PI3K family members.
| M.Wt | 415.50 | |
| Formula | C23H21D2N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-N-Methyl-8-(1-((2'-methyl-[4,5'-bipyrimidin]-6-yl-4',6'-d2)amino)propan-2-yl)quinoline-4-carboxamide |
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1. Harnor SJ, et al. ChemMedChem. 2017 Jun 21;12(12):895-900.
2. D. Boucher, R, et al. AACR; Abstract No. 3716.

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