You are here:Home-Chemical Inhibitors & Agonists-Cell Cycle/DNA Damage-DNA-PK-SU-11752
SU-11752

Chemical Structure : SU-11752

CAS No.: 688036-19-3

SU-11752 (SU11752)

Catalog No.: PC-61970Not For Human Use, Lab Use Only.

SU-11752 is a potent, selective inhibitor of DNA-PK, >500-fold selectivity over PI3Kγ, inhibits DNA double-strand break repair in cells and sensitizs ionizing radiation in cancer cells..

Packing Price Stock Quantity
100 mg Get quote
250 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SU-11752 is a potent, selective inhibitor of DNA-PK, >500-fold selectivity over PI3Kγ, inhibits DNA double-strand break repair in cells and sensitizs ionizing radiation in cancer cells.

Physicochemical Properties

M.Wt 493.57
Formula C26H27N3O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-[[1,2-Dihydro-2-oxo-5-[(phenylamino)sulfonyl]-3H-indol-3-ylidene]methyl]-2,4-diethyl-1H-pyrrole-3-propanoic acid

References

1. Ismail IH, et al. Oncogene. 2004 Jan 29;23(4):873-82.

2. Harnor SJ, et al. ChemMedChem. 2017 Jun 21;12(12):895-900.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: