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Chemical Structure : SU-11752
Catalog No.: PC-61970Not For Human Use, Lab Use Only.
SU-11752 is a potent, selective inhibitor of DNA-PK, >500-fold selectivity over PI3Kγ, inhibits DNA double-strand break repair in cells and sensitizs ionizing radiation in cancer cells.
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SU-11752 is a potent, selective inhibitor of DNA-PK, >500-fold selectivity over PI3Kγ, inhibits DNA double-strand break repair in cells and sensitizs ionizing radiation in cancer cells.
| M.Wt | 493.57 | |
| Formula | C26H27N3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ismail IH, et al. Oncogene. 2004 Jan 29;23(4):873-82.
2. Harnor SJ, et al. ChemMedChem. 2017 Jun 21;12(12):895-900.
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