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Chemical Structure : IC 87361
Catalog No.: PC-62995Not For Human Use, Lab Use Only.
IC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β.
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IC 87361 is a potent and selective DNA-PK inhibitor with IC50 of 34 nM, shows >50-fold selectivity over p110β; enhances radiation sensitivity in wild-type C57BL6 endothelial cells; induces radiosensitization of tumor microvasculature in wild-type mice.
| M.Wt | 323.348 | |
| Formula | C19H17NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kashishian A, et al. Mol Cancer Ther. 2003 Dec;2(12):1257-64.
2. Shinohara ET, et al. Cancer Res. 2005 Jun 15;65(12):4987-92.
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