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Chemical Structure : Compound 401
CAS No.: 168425-64-7
Catalog No.: PC-45615Not For Human Use, Lab Use Only.
A synthetic inhibitor of DNA-PK also inhibits mTOR (IC50=5.3 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $104 | In stock | |
| 50 mg | $368 | In stock | |
| 100 mg | $680 | In stock |
Bulk size, bulk discount!
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A synthetic inhibitor of DNA-PK also inhibits mTOR (IC50=5.3 uM); no inhibition on p110α/p85α PI3K (>100 uM); blocks the phosphorylation of S6 kinase 1 Thr389 and Akt Ser473 in COS7 cells.
| M.Wt | 281.3092 | |
| Formula | C16H15N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 6 mg/mL |
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| Chemical Name/SMILES |
4H-Pyrimido[2,1-a]isoquinolin-4-one, 2-(4-morpholinyl)- |
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1. Ballou LM, et al. J Biol Chem. 2007 Aug 17;282(33):24463-70.
2. Griffin RJ, et al. J Med Chem. 2005 Jan 27;48(2):569-85.
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