SN38023 | DNA-PK inhibitor | Probechem Biochemicals

Chemical Structure : SN38023

SN38023 (SN 38023)

Catalog No.: PC-20221Not For Human Use, Lab Use Only.

SN38023 is a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361 (Cat# PC-62995), SN38023 is metabolised to a potent DNA-PKi (IC87361) selectively in radioresistant hypoxic cells.

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Biological Activity

SN38023 is a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361 (Cat# PC-62995), SN38023 is metabolised to a potent DNA-PKi (IC87361) selectively in radioresistant hypoxic cells.

Physicochemical Properties

M.Wt	462.46
Formula	C24H22N4O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[(1-Methyl-2-nitro-1H-imidazol-5-yl)methoxy]-7-(4-morpholinyl)-2-phenyl-4H-1-benzopyran-4-one

References

1. Way Wua Wong, et al. Biochem Pharmacol. 2019 Nov;169:113641.

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SN38023 (SN 38023)

Biological Activity

Physicochemical Properties

References

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