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Cat. No. Product Name Information
PC-20606

NVS-MELK8a

MELK inhibitor

NVS-MELK8a (MELK8a) is a novel potent, and selective MELK inhibitor with IC50 of 2 nM.
PC-35237

MELK inhibitor 17

MELK inhibitor

MELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM, >100-fold selectivity over CHK1, CAMKK2, NUAK1 and ERK2.
PC-61764

JW-7-25-1

MELK inhibitor

JW-7-25-1 is a potent MELK inhibitor with biochemical IC50 of 5.0 nM, also inhibits PIK3CA, mTOR, GSK3A and CDK7 with CI50 of 5-60 nM.
PC-61763

HTH-01-091

MELK inhibitor

HTH-01-091 is a potent and selective, cell-permeable, ATP-competitive MELK inhibitor with biochemical IC50 of 10.5 nM.
PC-61630

KIN-281

MELK inhibitor

KIN-281 is a small molecule that inhibits multiple kinases including MELK and the non-receptor tyrosine kinase BMX with IC50 of 1.4 and 1.9 uM, respectively.
PC-70141

MELK inhibitor C1

MELK inhibitor

MELK inhibitor C1 is a potent small molecule inhibitor of MELK kinase activity with IC50 of 42 nM.
PC-70140

MELK-T1

MELK inhibitor

MELK-T1 (JNJ-47117096) is a cell-permeable, potent and selective inhibitor of MELK kinase domain with IC50 of 37 nM.
PC-70139

MELK-T1 hydrochloride

MELK inhibitor

MELK-T1 (JNJ-47117096) hydrochloride is a cell-permeable, potent and selective inhibitor of MELK kinase domain with IC50 of 37 nM.
PC-42114

NVS-MELK8a hydrochloride

MELK inhibitor

NVS-MELK8a hydrochloride (MELK8a hydrochloride) is a novel potent, and selective MELK inhibitor with IC50 of 2 nM.
PC-44481

OTS-167 hydrochloride

MELK inhibitor

OTSSP167 hydrochloride (OTS-167) is a highly potent, selective and orally active MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM.
PC-44480

OTS167

MELK inhibitor

OTSSP167 (OTS167) is a highly potent, selective and orally active MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM.

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