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Chemical Structure : CFI02
CAS No.: 273735-28-7
Catalog No.: PC-35123Not For Human Use, Lab Use Only.
CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 25 mg | $398 | In stock | |
| 100 mg | $798 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.
CFI02 reduces HCMV yield by >3 logs at 1 uM, and shows no inhibitory activity against closely related betaherpesviruses (including MCMV, simian CMV, and RCMV) (IC50>20 uM) as well as cytotoxic effect (CC50>50 uM).
| M.Wt | 491.43 | |
| Formula | C18H11F6N5OS2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(4-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)phenyl)-1,2,3-thiadiazole-4-carboxamide |
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1. Jones TR, et al. J Virol. 2004 Feb;78(3):1289-300.
2. Bloom JD, et al. Bioorg Med Chem Lett. 2003 Sep 1;13(17):2929-32.
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