Tomeglovir |CAS:233254-24-5 Probechem Biochemicals

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Chemical Structure : Tomeglovir

Tomeglovir (BAY 38-4766;BAY 384766)

Catalog No.: PC-61945Not For Human Use, Lab Use Only.

Tomeglovir (BAY 384766) is a potent, highly selective, nonnucleoside inhibitor of cytomegalovirus (CMV) replication.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Tomeglovir (BAY 384766) is a potent, highly selective, nonnucleoside inhibitor of cytomegalovirus (CMV) replication; selectively inhibits not only HCMV strains, including ganciclovir-resistant clinical isolates, but also a number of monkey and rodent cytomegaloviruses.

CMV Infection

Phase 2 Discontinued

Physicochemical Properties

M.Wt	441.546
Formula	C23H27N3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(((5-(Dimethylamino)-1-naphthyl)sulfonyl)amino)phenyl)-3-hydroxy-2,2-dimethylpropionamide

References

1. Weber O, et al. Antiviral Res. 2001 Mar;49(3):179-89.

2. Buerger I, et al. J Virol. 2001 Oct;75(19):9077-86.

3. Reefschlaeger J, et al. J Antimicrob Chemother. 2001 Dec;48(6):757-67.

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Tomeglovir (BAY 38-4766;BAY 384766)

Biological Activity

Physicochemical Properties

References

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