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Chemical Structure : Brincidofovir
CAS No.: 444805-28-1
Catalog No.: PC-62054Not For Human Use, Lab Use Only.
Brincidofovir (CMX 001, Cidofovir HDP) is a lipid conjugate of the acyclic nucleotide phosphonate, cidofovir that shows activity against all five families of dsDNA viruses that cause human morbidity and mortality, including orthopoxviruses such as variola virus, the cause of human smallpox.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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Brincidofovir (CMX 001, Cidofovir HDP) is a lipid conjugate of the acyclic nucleotide phosphonate, cidofovir that shows activity against all five families of dsDNA viruses that cause human morbidity and mortality, including orthopoxviruses such as variola virus, the cause of human smallpox.
Brincidofovir has a number of advantages for treatment of smallpox in an emergency including greater potency in vitro against all dsDNA viruses that cause human disease, a high genetic barrier to resistance, convenient oral administration as a tablet or liquid, and no evidence to date of nephrotoxicity in either animals or humans.
| M.Wt | 561.701 | |
| Formula | C27H52N3O7P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-(hexadecyloxy)propyl hydrogen ((((S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonate |
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1. Toth K, et al. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7293-7.
2. Lanier R, et al. Viruses. 2010 Dec;2(12):2740-2762.
3. McMullan LK, et al. Antiviral Res. 2016 Jan;125:71-8.
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