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Cidofovir

Chemical Structure : Cidofovir

CAS No.: 113852-37-2

Cidofovir (GS-0504;HPMPC;(S)-HPMPC)

Catalog No.: PC-45259Not For Human Use, Lab Use Only.

The prodrug of cidofovir diphosphate that inhibits cytomegalovirus (CMV) viral replication by selectively inhibiting viral DNA polymerases.

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Biological Activity

The prodrug of cidofovir diphosphate that inhibits cytomegalovirus (CMV) viral replication by selectively inhibiting viral DNA polymerases; also incorporates itself into viral DNA hence inhibiting viral DNA synthesis during reproduction.

CMV Infection

Approved

Physicochemical Properties

M.Wt 279.187
Formula C8H14N3O6P
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O: 6.4 mg/mL (Need warming)

Chemical Name/SMILES

Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-

References

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