Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Maribavir
CAS No.: 176161-24-3
Catalog No.: PC-38784Not For Human Use, Lab Use Only.
Maribavir (1263W94, Benzimidavir) is a potent and selective inhibitor of human cytomegalovirus (HCMV) replication with IC50 of 0.13 uM against laboratory strain AD169, and 0.03-0.13 uM against 10 clinical HCMV isolates.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $188 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Maribavir (1263W94, Benzimidavir) is a potent and selective inhibitor of human cytomegalovirus (HCMV) replication with IC50 of 0.13 uM against laboratory strain AD169, and 0.03-0.13 uM against 10 clinical HCMV isolates.
Maribavir (1263W94) is active against viral mutants that are resistant to GCV, CDV, and PFA.
Maribavir is orally bioavailable, and is the first and only antiviral agent that targets and inhibits the pUL97 protein kinase and its natural substrates.
| M.Wt | 376.234 | |
| Formula | C15H19Cl2N3O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(2S,3S,4R,5S)-2-(5,6-dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
|
1. Koszalka GW, et al. Antimicrob Agents Chemother. 2002 Aug;46(8):2373-80.
2. Gershburg E, et al. J Virol. 2002 Feb;76(3):998-1003.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
