Chemical Structure : Zabedosertib
CAS No.: 1931994-81-8
Catalog No.: PC-38683Not For Human Use, Lab Use Only.
Zabedosertib (BAY1834845) is a potent, selective IRAK4 inhibitor with IC50 of 3.4 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway.
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Zabedosertib (BAY1834845) is a potent, selective IRAK4 inhibitor with IC50 of 3.4 nM, inhibits IRAK4 mediated activation of the TLR/MYD88 pathway.
M.Wt | 470.47 | |
Formula | C20H21F3N4O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-{6-(2-hydroxypropan-2-yl)-2-[2-(methanesulfonyl)ethyl]- 2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2- carboxamide |
1. Bothe U, et al. J Med Chem. 2024 Jan 25;67(2):1225-1242.
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