| Cat. No. |
Product Name |
Information |
| PC-21921 |
BIO-7488
IRAK4 inhibitor
|
BIO-7488 (BIO7488) is the first potent, selective, and CNS-penetrant IRAK4 inhibitor with IC50 of 0.5 nM (1 mM ATP). |
| PC-43498 |
IRAK-1-4 Inhibitor I
|
IRAK-1-4 Inhibitor I is a potent, dual inhibitor of IRAK4 and IRAK1 with IC50 of 0.2 uM and 0.3 uM, respectively. |
| PC-43455 |
IRAK inhibitor 2
|
IRAK inhibitor 2 is a potent IRAK inhibitor.. |
| PC-43454 |
IRAK inhibitor 1
|
IRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, shows little to no activity against JNK-1 and JNK-2 with IC50 of 3.801 uM and >10 uM, respectively.. |
| PC-61623 |
IRAK4 inhibitor 23
|
A potent, selective, orally bioavailable IRAK4 inhibitor with IC50 of 7 nM. |
| PC-61091 |
PF-05388169
|
A potent, selective IRAK4 inhibitor with IC50 of 0.094 nM, >500-fold selectivity over IRAK1 (IC50=65 nM). |
| PC-60997 |
AS 2444697
|
A potent, selective, orally bioavailable IRAK-4 inhibitor that potently inhibits human and rat IRAK-4 activity with subnanomolar order, >30-fold selectivity over IRAK-1. |
| PC-60980 |
IRAK4-IN-16
|
A potent, selective, and orally bioavailable inhibitor of interleukin-1 receptor-associate kinase-4 (IRAK4) with IC50 of 2.8 nM, 217- and 892-fold selectivity over IRAK-1 and TAK1, respectively. |
| PC-70009 |
Thymoquinone
|
An anticancer phytochemical commonly found in black cumin. |
| PC-60013 |
IRAK4-IN-28
|
A novel potent, selective IRAK4 inhibitor with IC50 of 51 nM. |
