JH-XI-82-01

Chemical Structure : JH-XI-82-01

Catalog No.: PC-28200Not For Human Use, Lab Use Only.

JH-XI-82-01 is a potent, selective dual IRAK1/IRAK4 inhibitor with enzymetic IC50 of 3 nM and 7 nM respectively.

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Biological Activity

JH-XI-82-01 is a potent, selective dual IRAK1/IRAK4 inhibitor with enzymetic IC50 of 3 nM and 7 nM respectively.

M.Wt	456.55
Formula	C25H28N8O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(1-isopropylpiperidin-4-yl)-1-(pyridin-2-yl)-1H-pyrazol-5-yl)-6-(1H-pyrazol-5-yl)picolinamide

1. Hatcher JM, et al. ACS Med Chem Lett. 2026 Aug 26;17(9):1977-1988.