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KME-3859

Chemical Structure : KME-3859

CAS No.: 2968466-04-6

KME-3859 (KME3859)

Catalog No.: PC-21202Not For Human Use, Lab Use Only.

KME-3859 is a potent, selective IRAK4 inhibitor with IC50 of 5 nM, 100-fold selective over IRAK1.

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Purity & Documentation Purity: 99.16% (HPLC) Select Batch:

Biological Activity

KME-3859 is a potent, selective IRAK4 inhibitor with IC50 of 5 nM, 100-fold selective over IRAK1.

Physicochemical Properties

M.Wt 323.40
Formula C18H21N5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-6-(6-methoxyimidazo[1,2-a]pyridin-3-yl)-N-(piperidin-3-yl)pyridin-2-amine

References

1. Bennett J, et al. Blood. 2023 Sep 14;142(11):989-1007.

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