THZ-2-118 |CAS:1644498-54-3 Probechem Biochemicals

Chemical Structure : THZ-2-118

THZ-2-118 (IRAK1 inhibitor)

Catalog No.: PC-38076Not For Human Use, Lab Use Only.

THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM.
THZ-2-118 does not inhibitor IRAK4 at 10 uM, also potently inhibits JNK1/2/3 (IC50=1-2 nM).

Physicochemical Properties

M.Wt	493.571
Formula	C28H27N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-(4-(dimethylamino)but-2-enamido)-N-(4-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide

References

1. Hatcher JM, et al. ACS Med Chem Lett. 2020 Oct 9;11(11):2238-2243.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

THZ-2-118 (IRAK1 inhibitor)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.