| Cat. No. |
Product Name |
Information |
| PC-28014 |
B029-2
p300/CBP inhibitor
|
B029-2 (SYY-B029-2) is a potent p300/CBP histone acetyltransferase (HAT) inhibitor with IC50 of 0.49/7.1 nM for p300/CBP rspectively, shows anti-proliferation on ovarian cancer cell line OVCAR-3 with IC50 of 153 nM. |
| PC-26970 |
Butyrolactone 3
GCN5 inhibitor
|
Butyrolactone 3 (MB-3) is a specific, cell-permeable small-molecule inhibitor of histone acetyltransferase GCN5 with IC50 of 100 uM. |
| PC-26758 |
OP-3136
KAT6 inhibitor
|
Omvitrastat (OP-3136, OP3136) is a potent, selective and orally bioavailable histone lysine acetyltransferase (KAT6, KAT6A/B) inhibitor, demonstrates robust anti-tumor activity in preclinical models of prostate cancer, ovarian cancer, and non-small cell lung cancer (NSCLC), both in vitro and in vivo. |
| PC-24370 |
Curcumin
p300 inhibitor
|
Curcumin (Diferuloylmethane) is a specific p300/CREB-binding protein acetyltransferase, inhibits acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. |
| PC-24171 |
Prifetrastat
KAT6 inhibitor
|
Prifetrastat (PF-07248144, PF-8144) is a potent, selective histone acetyltransferase KAT6 (KAT6A/6B) inhibitor. |
| PC-23297 |
BAY-184
KAT6A/B inhibitor
|
BAY-184 is a potent, selective and in vivo-active KAT6A/B inhibitor with IC50 of 71/83 nM respectively. |
| PC-21986 |
EPIC-0628
HOTAIR-EZH2 inhibitor
|
EPIC-0628 (EPIC0628) is a selective and potent inhibitor that selectively disrupts the HOTAIR-EZH2 interaction and promotes ATF3 expression, enhances the temozolomide efficacy in glioblastoma. |
| PC-20778 |
C646
p300 inhibitor
|
C646 is a selective, competitive histone acetyltransferase (HAT) p300 inhibitor with Ki of 400 nM, less potent for other acetyltransferases. |
| PC-20777 |
MC4171
KAT8 inhibitor
|
MC4171 (KAT8 inhibitor 34) is a first-in-class, selective and reversible lysine acetyltransferase KAT8 inhibitor with IC50 of 8.1 uM and SPR Kd of 2.04 uM. |
| PC-49533 |
JG-2016
HAT1 inhibitor
|
JG-2016 is a small molecule inhibitor of histone acetyltransferase 1 (HAT1) with IC50 of 14.8 uM in the HAT1 acetylation assays. |
| PC-49530 |
DS-9300
EP300/CBP inhibitor
|
DS-9300 (DS9300) is a highly potent, selective and orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with IC50 of 28 nM, inhibits cellular acetylation of histone H3K27 (H3K27Ac) with IC50 of 54 nM. |
| PC-38649 |
DS17701585
EP300/CBP inhibitor
|
DS17701585 is a novel potent, highly selective EP300/CBP histone acetyltransferase inhibitor with IC50 of 0.15 uM. |
