| Cat. No. |
Product Name |
Information |
| PC-21996 |
beta-Amyloid (42-1) human
|
β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). β-Amyloid (42-1), human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. |
| PC-73428 |
Minzasolmin
α-synuclein inhibitor
|
Minzasolmin (UCB0599) is an orally bioavailable and brain-penetrant small molecule alpha-synuclein (ASYN) misfolding inhibitor, UCB0599 is a single enantiomer of NPT200-11 (Cat#PC-35764). |
| PC-38109 |
YX-I-1
Amyloid modulator
|
YX-I-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically inhibits amyloid formation. |
| PC-38108 |
YX-A-1
Amyloid modulator
|
YX-A-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically enhances amyloid formation. |
| PC-35764 |
NPT200-11
alpha-synuclein inhibitor
|
NPT200-11 is an orally bioavailable and brain penetrating alpha-synuclein (ASYN) misfolding and aggregation inhibitor. |
| PC-35683 |
SynuClean-D
α-synuclein inhibitor
|
SynuClean-D (SC-D) is a novel, small molecule inhibitor of α-synuclein (α-Syn) aggregation, incubation of 70 uM α-Syn with 100 uM SC-D impacted α-Syn aggregation in vitro, as monitored by Th-T fluorescence. |
| PC-35124 |
PBT434
α-synuclein inhibitor
|
PBT434 is a novel quinazolinone compound with effect of lowering cellular iron levels, prevents iron mediated neurodegeneration and α-synuclein toxicity in multiple models of Parkinson disease. |
| PC-63274 |
ELN484228
α-synuclein inhibitor
|
ELN484228 is a small molecule binder of α-synuclein that shows protective effect in cellular models of αSyn-mediated vesicular dysfunction. |
| PC-63202 |
TDI-2760
Aβ aggregation inhibitor
|
TDI-2760 is a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction (IC50=1.67 uM) but also retains potency toward the Aβ42 aggregation inhibition process. |
| PC-62602 |
ALZ-801
|
ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate, a small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor for the treatment of Alzheimer's disease.. |
| PC-62381 |
RH01386
α-synuclein inhibitor
|
RH01386 (ZPD-2) is a small molecule that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death, also is a small molecule inhibitor of α-Synuclein (α-Syn) aggregation, inhibits the aggregation of wild-type α-Syn and the A30P and H50Q familial variants in vitro. |
| PC-62066 |
MRS2481
Aβ inhibitor
|
MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity. |
