| Cat. No. |
Product Name |
Information |
| PC-21996 |
beta-Amyloid (42-1) human
|
β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42). β-Amyloid (42-1), human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. |
| PC-20458 |
CNB-001
Aβ inhibitor
|
CNB-001 is a pyrazole derivative of curcumin with neuroprotective properties, inhibits extracellular Aβ toxicity in hippocampal neurons with EC50 of 400 nM. |
| PC-38734 |
Senile plaques (SPs) probe BSB
Aβ-specific ligand
|
Senile plaques (SPs) probe BSB is a chemical probe that can detect accumulation of Aβ in senile plaques (SPs) in vivo, exhibits high binding affinity for Aβ aggregates in vitro (Ki=0.4 uM). |
| PC-38480 |
TAE-1
Amyloid-beta modulator
|
TAE-1 is a sym-triazine-derived aggregation modulator, destabilizes Aβ1-42 assembly and inhibits amyloid-β fibril formation, also inhibits acetylcholinesterase (AChE) activity in SH-SY5Y neuronal cells. |
| PC-38408 |
ALI6
Aβ-LilrB2 inhibitor
|
ALI6 (Fluspirilene, Aβ-LilrB2 interaction inhibitor 6) is a small molecule Aβ-LilrB2 interaction inhibitor with Ki of 320 nM, blocks LilrB2 induced cell attachment and inhibit toxicity of Aβ. |
| PC-73428 |
Minzasolmin
α-synuclein inhibitor
|
Minzasolmin (UCB0599) is an orally bioavailable and brain-penetrant small molecule alpha-synuclein (ASYN) misfolding inhibitor, UCB0599 is a single enantiomer of NPT200-11 (Cat#PC-35764). |
| PC-73339 |
Ro 90-7501
Aβ42 inhibitor
|
Ro 90-7501 is a prototypic inhibitor for Abeta42 (Aβ42) fibril formation, reduces Aβ42-induced cytotoxicity (EC50=2 uM), also enhances TLR3 and RLR agonist induced antiviral response. |
| PC-73134 |
Synucleozid
α-synuclein inhibitor
|
Synucleozid (NSC 377363) is a small molecule that targets the IRE structure and inhibits SNCA gene translation in cells, directly targets the α-synuclein mRNA 5'UTR at the designed site. |
| PC-73121 |
anle145c
Amyloid aggregation inhibitor
|
anle145c is a small molecule inhibitor of amyloid aggregation and formation, inhibits human islet amyloid polypeptide (hIAPP)-induced death of INS-1E cells. |
| PC-38109 |
YX-I-1
hIAPP modulator
|
YX-I-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically inhibits amyloid formation. |
| PC-38108 |
YX-A-1
hIAPP modulator
|
YX-A-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically enhances amyloid formation. |
| PC-35764 |
NPT200-11
alpha-synuclein inhibitor
|
NPT200-11 is an orally bioavailable and brain penetrating alpha-synuclein (ASYN) misfolding and aggregation inhibitor. |
