| Cat. No. |
Product Name |
Information |
| PC-73339 |
Ro 90-7501
Aβ42 inhibitor
|
Ro 90-7501 is a prototypic inhibitor for Abeta42 (Aβ42) fibril formation, reduces Aβ42-induced cytotoxicity (EC50=2 uM), also enhances TLR3 and RLR agonist induced antiviral response. |
| PC-73134 |
Synucleozid
α-synuclein inhibitor
|
Synucleozid (NSC 377363) is a small molecule that targets the IRE structure and inhibits SNCA gene translation in cells, directly targets the α-synuclein mRNA 5'UTR at the designed site. |
| PC-73121 |
anle145c
Amyloid aggregation inhibitor
|
anle145c is a small molecule inhibitor of amyloid aggregation and formation, inhibits human islet amyloid polypeptide (hIAPP)-induced death of INS-1E cells. |
| PC-38109 |
YX-I-1
hIAPP modulator
|
YX-I-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically inhibits amyloid formation. |
| PC-38108 |
YX-A-1
hIAPP modulator
|
YX-A-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically enhances amyloid formation. |
| PC-35764 |
NPT200-11
alpha-synuclein inhibitor
|
NPT200-11 is an orally bioavailable and brain penetrating alpha-synuclein (ASYN) misfolding and aggregation inhibitor. |
| PC-35683 |
SynuClean-D
α-synuclein inhibitor
|
SynuClean-D (SC-D) is a novel, small molecule inhibitor of α-synuclein (α-Syn) aggregation, incubation of 70 uM α-Syn with 100 uM SC-D impacted α-Syn aggregation in vitro, as monitored by Th-T fluorescence. |
| PC-35456 |
Leucomethylene blue mesylate
Tau aggregation inhibitor
|
Leucomethylene blue mesylate (Trx0237, LMTX, Hydromethylthionine) is a Tau aggregation inhibitor (TAI) with Ki of 0.12 uM for intracellular TAI activity. |
| PC-35455 |
TRx0237
Tau inhibitor
|
TRx0237 (Hydromethylthionine, Methylene blue) is a Tau aggregation inhibitor (TAI) with Ki of 0.12 uM for intracellular TAI activity. |
| PC-35140 |
CID 9998128
Aβ42 inhibitor
|
CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils. |
| PC-35124 |
PBT434
α-synuclein inhibitor
|
PBT434 (ATH434) is a novel quinazolinone compound with effect of lowering cellular iron levels, prevents iron mediated neurodegeneration and α-synuclein toxicity in multiple models of Parkinson disease. |
| PC-63274 |
ELN484228
α-synuclein inhibitor
|
ELN484228 is a small molecule binder of α-synuclein that shows protective effect in cellular models of αSyn-mediated vesicular dysfunction. |
