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CID 9998128

Chemical Structure : CID 9998128

CAS No.: 733807-13-1

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CID 9998128 (CID9998128)

Catalog No.: PC-35140Not For Human Use, Lab Use Only.

CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CID 9998128 is a potential multi-target drug for the Alzheimer's disease (AD), inhibits the Aβ42 amyloid fibrillization and is capable to clear Aβ42 fibrils.
    CID 9998128 strongly binds to both amyloid beta 42 (Aβ42) fibrils and β-secretase and the van der Waals interaction is dominating over the electrostatic interaction in binding affinity.

    Physicochemical Properties

    M.Wt 352.401
    Formula C21H16N6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine

    References

    1. Thai NQ, et al. ACS Chem Neurosci. 2018 May 18. doi: 10.1021/acschemneuro.8b00091.

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