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Chemical Structure : NPT200-11
CAS No.: 1802518-63-3
Catalog No.: PC-35764Not For Human Use, Lab Use Only.
NPT200-11 is an orally bioavailable and brain penetrating alpha-synuclein (ASYN) misfolding and aggregation inhibitor.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $388 | In stock | |
| 10 mg | $558 | In stock | |
| 25 mg | $898 | In stock | |
| 100 mg | Get quote |
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NPT200-11 ((Rac)-Minzasolmin, (Rac)-UCB0599) is an orally bioavailable and brain penetrating alpha-synuclein (ASYN) misfolding and aggregation inhibitor.
NPT200-11 reduced retinal alpha-synuclein pathology in cortex, reduced associated neuroinflammation (astrogliosis), normalized striatal levels of the dopamine transporter (DAT) and improved motor function in animal model of Parkinson's disease.
| M.Wt | 425.60 | |
| Formula | C23H31N5OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(1-(1H-indol-3-yl)hexan-2-yl)-2-(4-methylpiperazin-1-yl)thiazole-5-carboxamide |
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1. Price DL, et al. Sci Rep. 2018 Nov 1;8(1):16165.
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