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SO286

Chemical Structure : SO286

CAS No.: 70878-37-4

SO286 (SO-286)

Catalog No.: PC-27705Not For Human Use, Lab Use Only.

SO286 is a small molecule ubiquilin-2 (UBQLN2) inhibitor with SPR KD of 0.351 uM, binds to the STI1 region of UBQLN2, blocking its liquid-gel/solid transition and interaction with α-synuclein (α-syn), thereby suppressing α-syn aggregation, shows neuroprotective activity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SO286 is a small molecule ubiquilin-2 (UBQLN2) inhibitor with SPR KD of 0.351 uM, binds to the STI1 region of UBQLN2, blocking its liquid-gel/solid transition and interaction with α-synuclein (α-syn), thereby suppressing α-syn aggregation, shows neuroprotective activity.

Physicochemical Properties

M.Wt 596.59
Formula C34H28O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,2,3,6-tetra-O-benzoyl-muco-inositol

References

1. Takei T, et al. EMBO J. 2025 Nov;44(22):6527-6555.

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