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TAE-1

Chemical Structure : TAE-1

CAS No.: 1414469-59-2

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TAE-1 (Amyloid-β inhibitor)

Catalog No.: PC-38480Not For Human Use, Lab Use Only.

TAE-1 is a sym-triazine-derived aggregation modulator, destabilizes Aβ1-42 assembly and inhibits amyloid-β fibril formation, also inhibits acetylcholinesterase (AChE) activity in SH-SY5Y neuronal cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TAE-1 is a sym-triazine-derived aggregation modulator, destabilizes Aβ1-42 assembly and inhibits amyloid-β fibril formation, also inhibits acetylcholinesterase (AChE) activity in SH-SY5Y neuronal cells.

Physicochemical Properties

M.Wt 1128.583
Formula C39H51I3N6O9
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,2',2''-((4,4',4''-((1,3,5-triazine-2,4,6-triyl)tris(oxy))tris(benzoyl))tris(oxy))tris(N,N,N-trimethylethan-1-aminium) iodide

References

1. Veloso AJ, et al. ACS Chem Neurosci. 2013 Jun 19;4(6):924-9.

2. Veloso AJ, et al. Anal Chem. 2014 May 20;86(10):4901-9.

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