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Chemical Structure : FPS-ZM1
CAS No.: 945714-67-0
Catalog No.: PC-45627Not For Human Use, Lab Use Only.
FPS-ZM1 is a high-affinity RAGE-specific inhibitor with Ki of 25 nM, blocks Aβ binding to the V domain of RAGE and inhibits Aβ40- and Aβ42-induced cellular stress in RAGE-expressing cells in vitro and in the mouse brain in vivo.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $118 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $298 | In stock | |
| 250 mg | Get quote |
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FPS-ZM1 is a high-affinity RAGE-specific inhibitor with Ki of 25 nM, blocks Aβ binding to the V domain of RAGE and inhibits Aβ40- and Aβ42-induced cellular stress in RAGE-expressing cells in vitro and in the mouse brain in vivo.
| M.Wt | 327.8478 | |
| Formula | C20H22ClNO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Benzamide, 4-chloro-N-cyclohexyl-N-(phenylmethyl)- |
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1. Deane R, et al. J Clin Invest. 2012 Apr;122(4):1377-92.
2. Hong Y, et al. Neurochem Res. 2016 May;41(5):1192-9.
3. Kwak T, et al. Oncogene. 2017 Mar;36(11):1559-1572.
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