DDQ | Aβ-Drp1 inhibitor | Probechem Biochemicals

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Chemical Structure : DDQ

DDQ (Aβ-Drp1 inhibitor DDQ)

Catalog No.: PC-21401Not For Human Use, Lab Use Only.

DDQ is a small molecule inhibitor of binding sites of Amyloid beta (Aβ) and Drp1, reduces interaction between Aβ and Drp1, shows anti-aging effects.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

DDQ is a small molecule inhibitor of binding sites of Amyloid beta (Aβ) and Drp1, reduces interaction between Aβ and Drp1, shows anti-aging effects.
DDQ also inhibits abnormal protein-protein interactions, such as Aβ and Drp1 and P-tau and Drp1.
DDQ is capable of reducing abnormal protein-protein interactions and protecting neurons from mutant protein(s)-induced toxicities.
DDQ reduces age-related insults, oxidative stress, and mitochondrial dysfunction.

Physicochemical Properties

M.Wt	430.44
Formula	C22H27N2O5P
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl ((S)-((3,4-dihydroxyphenethyl)amino)(quinolin-4-yl)methyl)(methoxymethyl)phosphinate

References

1. Murali Vijayan, et al. Mol Neurobiol. 2021 Jul;58(7):3588-3600.

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DDQ (Aβ-Drp1 inhibitor DDQ)

Biological Activity

Physicochemical Properties

References

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