TZ095 | Aβ fluorescent probe | Probechem Biochemicals

Chemical Structure : TZ095

TZ095 (TZ-095)

Catalog No.: PC-23221Not For Human Use, Lab Use Only.

TZ095 is a coumarin-based Aβ fluorescent probe for precise Aβ detection, exhibits remarkable affinity with Aβ aggregates (Kd = 81.54 nM for oligomers; Kd = 66.70 nM for fibril) and substantial fluorescence enhancement (F/F0 = 44).

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Biological Activity

Physicochemical Properties

M.Wt	316.36
Formula	C20H16N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-7-(4-(dimethylamino)styryl)-2-oxo-2H-chromene-3-carbonitrile

References

1. You H, et al. Eur J Med Chem. 2024 Nov 15;278:116800.

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TZ095 (TZ-095)

Biological Activity

Physicochemical Properties

References

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