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ABD0171

Chemical Structure : ABD0171

CAS No.: 2595201-23-1

ABD0171 (ABD-0171)

Catalog No.: PC-25912Not For Human Use, Lab Use Only.

ABD0171 (ABD-0171) is a potent, selective and irreversible ALDH1A3 inhibitor with additional ALDH1A1 activity, disrupts key oncogenic pathways, including IL6/JAK/STAT3, tPA, and Src/FAK, resulting in robust antitumor and antimetastatic effects in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ABD0171 (ABD-0171) is a potent, selective and irreversible ALDH1A3 inhibitor with additional ALDH1A1 activity, disrupts key oncogenic pathways, including IL6/JAK/STAT3, tPA, and Src/FAK, resulting in robust antitumor and antimetastatic effects in vitro and in vivo.

Physicochemical Properties

M.Wt 333.49
Formula C19H27NO2S:
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Pentynethioic acid, 4-[[2-[(3,4-dimethylphenyl)methoxy]ethyl]methylamino]-4-methyl-, S-methyl ester

References

1. Pequerul R, et al. Cell Chem Biol. 2025 Oct 16;32(10):1260-1278.e12.

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