Disulfiram | ALDH1 inhibitor | Probechem Biochemicals

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Chemical Structure : Disulfiram

CAS No.: 97-77-8

Disulfiram (Tetraethylthiuram disulfide, TETD)

Catalog No.: PC-22705Not For Human Use, Lab Use Only.

Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1) with IC50 of 0.13 uM for ALDH1A1 and 3.4 uM for ALDH2, also inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	296.52
Formula	C10H20N2S4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Bis(diethylthiocarbamoyl) disulfide

References

1. Lipsky J.J., et al. Chem. Biol. Interact. 2001;130–132:93–102.

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Disulfiram (Tetraethylthiuram disulfide, TETD)

Biological Activity

Physicochemical Properties

References

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