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You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Aldehyde Dehydrogenase (ALDH)-AD-5591
AD-5591

Chemical Structure : AD-5591

CAS No.: 1804942-45-7

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AD-5591 (AD5591, AD 5591)

Catalog No.: PC-21250Not For Human Use, Lab Use Only.

AD-5591 (AD5591) is a potent, selective, new generation small molecule ALDH2 activator, has the improved biological activities and pharmacological properties compared to Alda-1.

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2 mg $248 In stock
5 mg $398 In stock
10 mg $588 In stock
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Purity & Documentation Purity: 99.19% (HPLC) Select Batch:

Biological Activity

AD-5591 (AD5591) is a potent, selective, new generation small molecule ALDH2 activator, has the improved biological activities and pharmacological properties compared to Alda-1.
AD-5591 (100  μM) significantly increases the enzymatic activity of recombinant WT and mutant human ALDH2 proteins.
AD-5591 is the active form of AD-9308.

Physicochemical Properties

M.Wt 438.50
Formula C25H27FN2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(3-fluoro-4-methoxybenzyl)-5-(3-(hydroxymethyl)pyridin-2-yl)-2-isobutoxybenzamide

References

1. Chang YC, et al. Nat Commun. 2023 Sep 25;14(1):5971.

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